galanin receptors การใช้

Galanin receptors can be found throughout the peripheral and central nervous systems and the endocrine system.
Galanin receptors are expressed in the central nervous system, in the pancreas, and on solid tumours.
Galanin receptors are seven-trans membrane proteins shown to activate a variety of intracellular second-messenger pathways.
The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways.
Selective galanin agonists are anticonvulsant, while antagonists produce antidepressant and anxiolytic effects in animals, so either agonist or antagonist ligands for the galanin receptors may be potentially therapeutic compounds in humans.